A new strategy to protect against HIV infection A highly effective vaccine against HIV-1 remains elusive, but one promising strategy targets designer antibodies which have much broader potency than most regular, specific antibodies exquisitely. These broadly neutralizing antibodies are designed for the high mutation rate of HIV particles that makes normal, very specific antibodies worthless within a short space of period generic cialis canada . A report published by Cell Press on March 28th in the journal Cell reveals amazing mutations in these antibodies that are crucial for strong protection against HIV-1.
The researchers discovered that two independent groups of cells generate the same signal by different pathways and these cells subsequently take action together to send out the signal to the target cell. This way, the signal is received by the receptor cell from two distinct sources. Using RNA interference techniques , the experts observed that it was essential to disactivate the signal in both sets of cells to be able to avoid the message from becoming sent. In addition they observed that overstimulating signal production created problems in the receptor cell, causing it to develop incorrectly.