Trial Design This trial was a global, randomized, open-label, Stage 3 trial to evaluate the basic safety and efficacy of talimogene laherparepvec compared to a control therapy with GM-CSF in over 400 individuals with unresected stage IIIB, IV or IIIC melanoma. Treatment could last for up to 18 months. Where appropriate, responding or stable patients could receive extra treatment about an extension protocol.. AMGEN announces additional results from talimogene laherparepvec Stage 3 trial AMGEN today announced additional results from a pivotal Phase 3 trial evaluating talimogene laherparepvec in patients with unresected stage IIIB, IIIC or IV melanoma in comparison to granulocyte-macrophage colony-stimulating aspect .Copyright 2009 Advisory Board Business and Kaiser Family Foundation. All rights reserved.. Allscripts approves Apixio Community Search product Apixio Inc., the leading provider of scientific integration and smart search solutions for personal health data medically, announced that it is Community Search item has been tested and approved by Allscripts and is now featured in the Allscripts Program Store and Exchange on the business’s ClientConnect website. Apixio is definitely on the market for users of Sunrise Clinical Manager 5.5.S. Is usually trending towards delivering higher quality and more cost effective care, and Apixio’s option when coupled with Sunrise from Allscripts can help healthcare organizations attain these goals.