Julia E. Maxson, Ph Cavemen ancestors food .D., Jason Gotlib, M.D., Daniel A. Pollyea, M.D., Angela G. Fleischman, M.D., Ph.D., Anupriya Agarwal, Ph.D., Christopher A. Eide, B.A., Daniel Bottomly, M.S., Beth Wilmot, Ph.D., Shannon K. McWeeney, Ph.D., Cristina E. Tognon, Ph.D., J. Blake Pond, M.S., Robert H. Collins, M.D., Basem Goueli, M.D., Ph.D., Stephen T. Oh, M.D., Ph.D., Michael W. Deininger, M.D., Ph.D., Bill H. Chang, M.D., Ph.D., Marc M. Loriaux, M.D., Ph.D., Brian J. Druker, M.D., and Jeffrey W. Tyner, Ph.D.: Oncogenic CSF3R Mutations in Chronic Neutrophilic Leukemia and Atypical CML Therapy with small-molecule kinase inhibitors offers improved the outcomes in sufferers who have certain types of tumor with kinase-pathway dependence caused by defined genetic abnormalities.1,2 Extrapolation of this model to additional cancers requires knowledge of operationally important genetic mutations that result in corresponding activation of kinase pathways.
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