Through the 4th quarters of 2013 and 2012, AcelRx recognized income of $27.6 million and $1.7 million, respectively.4 million of revenue recognized from the $30.0 million upfront payment from Grunenthal and $0.2 million of reimbursement for work completed under a research grant from the U.S. Army Medical Study and Materiel Order , for development of ARX-04. 4th quarter of 2012 income contains $1.7 million in reimbursement for work linked to the USAMRMC grant. Research and development expenditures for the quarter ended December 31, 2013 totaled $4.3 million, weighed against $7.december 31 8 million for the quarter ended, 2012. Selling, general and administrative expenses had been $3.3 million for the fourth quarter of 2013, weighed against $1.9 million for the fourth quarter of 2012, due to an increase in commercial activities related to Zalviso primarily, including increased market research activities and the original build of internal advertising capabilities.What Does an Acne Scar Look Like? Acne scarring create in locations where former cystic pimple patches have been present. Scarring comes in three types 1. Atrophic, which are mostly shallow 2. Boxcar-designed 3. Ice pick-shaped, which are narrow and further. People with further pores and skin may also observe darkening within the marks, while people with less heavy epidermis may show inflammation within the scars. What Creates Pimples Even worse? Sun Exposing scars to they may be caused by sunlight to color and slowly the recovery process. How? Ultra violet radiation activate melanocytes , resulting in further yellowing. Your most secure bet: Prior to going outside, easy on a broad-spectrum sun block with an SPF of 15 or more, with the physical blocker zinc oxide, and refocus every two hours.