Sold by Roche beneath the brand name Accutane.

90 percent of dermatologists report having problems with Isotretinoin drug registry The web FDA tracking database iPledge – – with which everyone taking the acne drug isotretinoin, sold by Roche beneath the brand name Accutane, need to register to receive their prescriptions – – has caused problems for approximately 90 percent of dermatologists, according to a survey commissioned by the American Academy of Dermatology and released Mon, the AP/Sacramento Bee reports . Research have shown that isotretinoin can cause severe unwanted effects in women that are pregnant, such as birth defects and fetal death, and also might cause depression and suicide. FDA in 2004 released data that demonstrated that strict measures enacted to lessen the number of birth defects linked to isotretinoin had little effect on the number of women who take the medication while pregnant ed cure .

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