‘Everything is in order’ is the biggest lie of all, uttered by governments that are nearly universally bankrupt and incompetent repeatedly. The truly big lie everyone believes is usually the proven fact that no radical and unexpected adjustments can ever happen – – that things will continue on the method they’ve been for the easy cause that they’ve always been that way. Few people can imagine a global without fossil fuels; with out a functioning power grid; with out a 911 crisis responder system that features; without inexpensive and easy meals appearing on food markets shelves magically, etc. So the citizens of the globe will greedily drink down the last drop of drinking water remaining.Additional information on study participants are available in the protocol, obtainable with the entire text of this article at NEJM.org. Study Design and Oversight This randomized, active-comparator, placebo-controlled, between December 2008 and June 2011 double-blind trial was executed at 102 sites in the usa and Europe. The scholarly study was sponsored by Pfizer. All the authors were involved in the design and overall performance of the study, which was conducted according to the Declaration of Helsinki.