Maria-Isabel Covas.

D., Ph.D ., Emilio Ros, M.D., Ph.D.D., Ph.D., Maria-Isabel Covas, D.Pharm., Ph.D., Dolores Corella, D.Pharm., Ph.D.D., Ph.D.D., Ph.D.D., Miquel Fiol, M.D., Ph.D.D., Ph.D., Rosa Maria Lamuela-Raventos, D.Pharm., Ph.D.D., Ph.D.D., Ph.D., Josep Basora, M.D., Ph.D.D., Ph.D.D., Ph.D.Pharm, M.D., Ph.D.D., Ph.D. For the PREDIMED Study Investigators: Primary Prevention of CORONARY DISEASE with a Mediterranean Diet The original Mediterranean diet is seen as a a higher intake of essential olive oil, fruit, nuts, vegetables, and cereals; a moderate intake of fish and poultry; a minimal intake of milk products, red meat, processed meats, and sweets; and wines in moderation, consumed with foods.1 In observational cohort studies2,3 and a secondary prevention trial ,4 increasing adherence to the Mediterranean diet plan has been beneficial regarding cardiovascular risk consistently.2-4 A systematic review ranked the Mediterranean diet as the most most likely dietary model to supply protection against coronary heart disease.5 Little clinical trials possess uncovered plausible biologic mechanisms to describe the salutary effects of this food pattern.6-9 We designed a randomized trial to check the efficacy of two Mediterranean diets , as compared with a control diet , on principal cardiovascular prevention.

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